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Test ID TYRSC Tyrosinemia Follow-Up Panel, Self-Collect, Blood Spot


Necessary Information


1. Patient's age is required.

2. Patient's street address, city, state, ZIP (postal) code, country, and home phone are required (post-office [PO] boxes are not acceptable delivery locations).



Specimen Required


Container/Tube: Blood Spot Card

Specimen Volume: 2 Blood spots

Additional Information:

1. Order test each time the patient is to collect a dried blood specimen at home and mail the specimen directly to Mayo Clinic Laboratories.

2. Order should be placed a minimum of 3 days prior to desired date of collection.

3. Enter patient's address information for each order created, including street address (post-office [PO] boxes are not acceptable delivery locations), city, state abbreviation, zip code, country, and home phone number.

4. For each order, the Blood Spot Collection-Self Collect kit will be mailed directly to the patient for self-collection (delivery to a PO box will not occur).

5. For more information on how to collect blood spots, see the following

-How to Collect a Dried Blood Spot Sample via fingerstick

-Blood Spot Collection Instructions-Fingerstick

-Blood Spot Collection Instructions-Fingerstick-Spanish


Secondary ID

610495

Useful For

Monitoring of individuals with tyrosinemia type I (hepatorenal tyrosinemia) using a patient-collected specimen

Specimen Type

Whole blood

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Ambient (preferred) 7 days FILTER PAPER
  Frozen  90 days FILTER PAPER
  Refrigerated  14 days FILTER PAPER

Reject Due To

Blood spot specimen that shows serum rings or has multiple layers Reject
Insufficient specimen Reject
Unapproved filter papers Reject

Reference Values

Tyrosine:

<4 weeks: 40-280 nmol/mL

≥4 weeks: 25-150 nmol/mL

 

Phenylalanine: 27-107 nmol/mL

 

Methionine: 11-45 nmol/mL

 

Succinylacetone: ≤1.0 nmol/mL

 

Nitisinone: ≤0.5 nmol/mL

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

0383U

Day(s) Performed

Monday through Friday

Report Available

3 to 5 days