Test ID RISA Risankizumab, Serum
Ordering Guidance
Risankizumab trough levels may be useful to document therapeutic levels and to assess lack of response. For patients not responding properly to therapy, a risankizumab level could aid in the decisions to escalate, de-escalate, or discontinue risankizumab.
Specimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Draw blood immediately before the next scheduled dose (trough specimen).
2. Within 2 hours of collection, centrifuge and aliquot serum into plastic vial.
Secondary ID
621304Useful For
Assessing the response to risankizumab therapy
Assessing the need for dose escalation
Evaluating potential changes or discontinuation of therapy
Monitoring patients who need to be above a certain risankizumab concentration to improve the odds of a clinical response for therapy optimization
Specimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Lipemia | Reject |
| Gross icterus | OK |
Reference Values
Lower limit of quantitation=1.0 mcg/mL
Day(s) Performed
Varies
Report Available
2 to 9 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80299
Testing Algorithm
For information see Ulcerative Colitis and Crohn Disease Therapeutic Drug Monitoring Algorithm.
Special Instructions
Forms
If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen.