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Test ID RETB Reticulocyte Profile, Blood


Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Secondary ID

616856

Useful For

Assessing erythropoietic bone marrow activity in anemia and other hematologic conditions

 

Assessment of acute iron deficiency

 

Monitoring early response to iron therapy or erythropoiesis-stimulating agents

 

Early monitoring of therapy for nutritional anemias (eg, megaloblastic, iron deficiency) where immature reticulocyte fraction precedes reticulocyte count increase by several days

 

Monitoring therapeutic efficacy of erythropoietin treatment

 

Monitoring early engraftment after bone marrow transplantation

Specimen Type

Whole Blood EDTA

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 48 hours
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK
Clotted Reject

Reference Values

% RETICULOCYTES

1-3 days: 3.47-5.40%

4 days-4 weeks: 1.06-2.37%

5 weeks-7 weeks: 2.12-3.47%

8 weeks-5 months: 1.55-2.70%

6 months-23 months: 0.99-1.82%

24 months-5 years: 0.82-1.45%

6-11 years: 0.98-1.94%

12-17 years: 0.90-1.49%

Adults: 0.60-2.71%

 

ABSOLUTE RETICULOCYTES

1-3 days: 147.5-216.4 x 10(9)/L

4 days-4 weeks: 51.3-110.4 x 10(9)/L

5 weeks-7 weeks: 51.8-77.9 x 10(9)/L

8 weeks-5 months: 48.2-88.2 x 10(9)/L

6 months-23 months: 43.5-111.1 x 10(9)/L

24 months-5 years: 36.4-68.0 x 10(9)/L

6-11 years: 42.4-70.2 x 10(9)/L

12-17 years: 41.6-65.1 x 10(9)/L

Adults: 30.4-110.9 x 10(9)/L

 

IMMATURE RETICULOCYTE FRACTION (IRF)

1-3 days: 30.5-35.1%

4 days-4 weeks: 14.5-24.6%

5 weeks-2 months: 19.1-28.9%

3-5 months: 13.4-23.3%

6 months-<2 years: 11.4-25.8%

2-<6 years: 8.4-21.7%

6-<12 years: 8.9-24.1%

12-<18 years: 9.0-18.7%

≥ 18 years:

Female:3.0-15.9%

Male: 2.3-13.4%

 

RETICULOCYTE HEMOGLOBIN

Males:

1 day-5 months: 27.6-38.7 pg

6 months-<2 years: 28.7-35.7 pg

2-<6 years: 27.7-37.8 pg

6-<12 years: 32.4-37.6 pg

12-<18 years: 30.0-37.6 pg

Adults: 30.0-37.6 pg

 

Females:

1 day-5 months: 29.2-37.5 pg

6 months-<2 years: 30.1-35.7 pg

2-<6 years: 29.3-37.3 pg

6-<12 years: 30.4-39.7 pg

12-<18 years: 30.0-37.6 pg

Adults: 30.0-37.6 pg

 

RED BLOOD CELL COUNT (RBC)

Males:

0-14 days: 4.10-5.55 x 10(12)/L

15 days-4 weeks: 3.16-4.63 x 10(12)/L

5 weeks-7 weeks: 3.02-4.22 x 10(12)/L

8 weeks-5 months: 3.43-4.80 x 10(12)/L

6 months-23 months: 4.03-5.07 x 10(12)/L

24 months-35 months: 3.89-4.97 x 10(12)/L

3-5 years: 4.00-5.10 x 10(12)/L

6-10 years: 4.10-5.20 x 10(12)/L

11-14 years: 4.20-5.30 x 10(12)/L

15-17 years: 4.30-5.70 x 10(12)/L

Adults: 4.35-5.65 x 10(12)/L

 

Females:

0-14 days: 4.12-5.74 x 10(12)/L

15 days-4 weeks: 3.32-4.80 x 10(12)/L

5 weeks-7 weeks: 2.93-3.87 x 10(12)/L

8 weeks-5 months: 3.45-4.75 x 10(12)/L

6 months-23 months: 3.97-5.01 x 10(12)/L

24 months-35 months: 3.84-4.92 x 10(12)/L

3-5 years: 4.00-5.10 x 10(12)/L

6-10 years: 4.10-5.20 x 10(12)/L

11-14 years: 4.10-5.10 x 10(12)/L

15-17 years: 3.80-5.00 x 10(12)/L

Adults: 3.92-5.13 x 10(12)/L

Day(s) Performed

Monday through Sunday

Report Available

1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

85046

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Kidney Transplant Test Request

-Benign Hematology Test Request (T755)