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HelpTest ID PLPMA Prolactin, Pituitary Macroadenoma, Serum
Useful For
Quantifying prolactin in serum specimens where the high-dose hook effect is suspected (eg, presence of pituitary tumor with symptoms of prolactinoma, and lower than expected serum prolactin concentration)
Testing Algorithm
A pituitary adenoma should be identified by imaging studies prior to ordering this test.
Specimen Type
SerumOrdering Guidance
For initial patient assessment; order PRL / Prolactin, Serum as the screening test.
Necessary Information
Patient's age and sex are required.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 90 days | |
| Ambient | 24 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Males
<18 years: not established
≥18 years: 4.0-15.2 ng/mL
Females:
<18 years: not established
≥18 years: 4.8-23.3 ng/mL
Day(s) Performed
Report Available
Same day/1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84146
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.