Test ID PK1 Pyruvate Kinase Enzyme Activity, Blood
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Lavender top (EDTA)
Specimen Volume: 6 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Secondary ID
607459Useful For
Evaluation of nonspherocytic hemolytic anemia
Evaluation of neonatal anemia or jaundice
Evaluation of unexplained noninfectious hepatic failure
Evaluation of unexplained iron overload
Evaluation of unusually severe hemoglobin S trait
Evaluation of unusually severe glucose 6-phosphate dehydrogenase deficiency
Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling
Specimen Type
Whole Blood ACD-BSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood ACD-B | Refrigerated | 20 days |
Reject Due To
| Gross hemolysis | Reject |
| Fully clotted | Reject |
Reference Values
≥12 months of age: 5.5-12.4 U/g Hb
Reference values have not been established for patients younger than 12 months.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84220
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysForms
If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.