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HelpTest ID MTXSG Methotrexate Post Glucarpidase, Serum
Useful For
Monitoring methotrexate concentrations post-glucarpidase therapy
Documenting failure to respond that may be due to noncompliance
Guiding dosage adjustments in patients with kidney failure
Specimen Type
SerumShipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Amber vial
Specimen Volume: 1 mL serum
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into an amber vial.
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | LIGHT PROTECTED |
| Frozen | 14 days | LIGHT PROTECTED | |
| Ambient | 7 days | LIGHT PROTECTED |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
| Exposed to light >24 hours | Reject |
Reference Values
Nontoxic drug concentration after 72 hours: <0.1 mcmol/L
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 dayPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80204
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.