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HelpTest ID IETG Interference Evaluation Heterophile, Thyroglobulin Tumor Marker, Serum
Ordering Guidance
If interference or heterophile testing is not required, order HTG2 / Thyroglobulin, Tumor Marker, Serum.
For fine-needle aspirate specimens, order TFNAB / Thyroglobulin, Tumor Marker, Fine-Needle Aspiration Biopsy Needle Wash.
Specimen Required
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2.5 mL Serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Secondary ID
610069Useful For
Evaluation of suspected interference from heterophile antibodies causing a falsely elevated thyroglobulin result
Testing Algorithm
Heterophile antibody evaluation consists of comparison of thyroglobulin (Tg) concentrations obtained by immunoassay with the following:
-Tg concentrations following pretreatment with commercial heterophile blocking reagents
-Tg concentrations obtained by mass spectrometry
-Tg concentrations obtained by serial dilutions of the sample
In all samples, the presence of antithyroglobulin antibodies is evaluated.
Specimen Type
Serum RedSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 7 days |
| Frozen | 30 days | |
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
Reference Values
THYROGLOBULIN TUMOR MARKER
≤33 ng/mL
THYROGLOBULIN, MASS SPECTROMETRY
≤33 ng/mL
THYROGLOBULIN ANTIBODY
<1.8 IU/mL
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Report Available
3 to 6 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84432
86800
84432