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Test ID HBCRQ Hepatitis B Virus Core-Related Antigen, Quantitative, Serum


Ordering Guidance


This test should be requested only in individuals with all the following:

-Chronic hepatitis B

-Confirmed positive hepatitis B surface (HBs) antigen

-Negative hepatitis B e antigen (HBeAg)

-Positive hepatitis B e antibody (anti-HBe)

-Undetectable or low hepatitis B viral DNA levels (eg, <500 IU/mL) in serum



Additional Testing Requirements


Testing for hepatitis B virus (HBV) DNA (HBVQN / Hepatitis B Virus [HBV] DNA Detection and Quantification by Real-Time PCR, Serum) and surface antigen (HBAGQ / Hepatitis B Virus Surface Antigen, Quantitative, Serum) levels in serum will be helpful in monitoring response to curative antiviral therapy for chronic hepatitis B.



Shipping Instructions


Ship specimen frozen on dry ice only. If shipment will be delayed for more than 24 hours, freeze serum at -20 degrees to -80° C (up to 60 days) until shipment, and transport on dry ice.



Necessary Information


Collection date is required.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial


Secondary ID

621765

Useful For

Monitoring of response to antiviral therapy in individuals with chronic hepatitis B who are negative for hepatitis B e antigen (HBeAg), positive for hepatitis B e antibody, and undetectable or low hepatitis B virus DNA levels (eg, <500 IU/mL) in serum

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 28 days
  Refrigerated  14 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

<1,000 U/mL

Day(s) Performed

Tuesday

Report Available

1 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82397

Forms

f not ordering electronically, complete, print, and send 1 of the following:

-Gastroenterology and Hepatology Test Request (T728)

-Infectious Disease Serology Test Request (T916)