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Test ID GP210 GP210 Antibody, IgG, Serum


Additional Testing Requirements


This is a first line test when primary biliary cholangitis is strongly suspected. This test should be ordered in conjunction with testing for mitochondrial antibodies (M2) (AMA / Mitochondrial Antibodies [M2], Serum), SP100 antibodies (SP100 / SP100 Antibody, IgG, Serum), and antinuclear antibodies (NAIFA / Antinuclear Antibodies, HEp-2 Substrate, IgG, Serum).



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

620726

Useful For

Evaluating the risk of primary biliary cholangitis in anti-mitochondrial antibody (AMA)-negative patients by identification of gp210 antibodies

 

Estimating risk in AMA-positive patients with incomplete feature of disease

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
Heat-treated specimens Reject

Reference Values

Negative: ≤20.0 Units

Equivocal: 20.1-24.9 Units

Positive: ≥25.0 Units

Day(s) Performed

Tuesday

Report Available

2 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83516

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.

Testing Algorithm

For information see First-Line Screening for Autoimmune Liver Disease Algorithm.