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Test ID FLCS Immunoglobulin Free Light Chains, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

608250

Useful For

Monitoring serum from patients with monoclonal light chain diseases without a M-protein.

 

May be useful as a diagnostic test in patients in whom there is a suspicion of primary systemic amyloidosis, light chain deposition disease, or non-secretory myeloma

Testing Algorithm

The following algorithms are available:

-Amyloidosis: Laboratory Approach to Diagnosis

-Multiple Myeloma: Laboratory Screening

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

Reference Values

KAPPA-FREE LIGHT CHAIN

0.61-4.02 mg/dL

 

LAMBDA-FREE LIGHT CHAIN

0.67-3.46 mg/dL

 

KAPPA/LAMBDA FLC RATIO

0.57-2.45

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83521 x 2

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Hematopathology/Cytogenetics Test Request (T726)

-Renal Diagnostics Test Request (T830)

-Kidney Transplant Test Request