Sign in →

Test ID DRVI2 Dilute Russell's Viper Venom Time (DRVVT) Mix Ratio, Plasma


Ordering Guidance


Because no single coagulation test can identify or exclude all lupus anticoagulants (LA), and because of the complexity of testing LA, one of the following Coagulation Consultation reflexive panel procedures are recommended if clinically indicated:

ALUPP / Lupus Anticoagulant Profile, Plasma

AATHR / Thrombophilia Profile, Plasma and Whole Blood

APROL / Prolonged Clot Time Profile, Plasma



Additional Testing Requirements


Serum anticardiolipin antibody testing (CLPMG / Phospholipid [Cardiolipin] Antibodies, IgG and IgM, Serum) and anti-beta-2 glycoprotein I (B2GMG / Beta-2 Glycoprotein 1 Antibodies, IgG and IgM, Serum) antibody testing should also be performed in conjunction with coagulation-based testing for lupus anticoagulants to enhance detection of different types of antiphospholipid antibodies.



Specimen Required


Only orderable as a reflex. For more information see DRVI1 / Dilute Russell's Viper Venom Time (DRVVT), with Reflex, Plasma.

 

Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Platelet poor plasma

Collection Instructions:

1. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.

2. Centrifuge, transfer all plasma into a plastic vial and centrifuge plasma again.

3. Aliquot into a separate plastic vial, leaving 0.25 mL in the bottom of the centrifuged vial.

4. Immediately freeze plasma (no longer than 4 hours after collection) at -20° C or, ideally, -40° C or below.


Secondary ID

602180

Useful For

Detecting the presence or helping to exclude the presence of lupus anticoagulants (LAs)

 

Identifying LAs that do not prolong the activated partial thromboplastin time (APTT)

 

Evaluating unexplained prolongation of the APTT or prothrombin time clotting tests

 

Distinguishing LA from a specific coagulation factor inhibitor or coagulation factor deficiencies

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Reference Values

Only orderable as part of a reflex. For more information see DRVI1 / Dilute Russell's Viper Venom Time (DRVVT), with Reflex, Plasma.

 

<1.20

Normal ranges for children: Not clearly established but similar to normal ranges for adults, except for newborn infants whose results may not reach adult values until age 3 to 6 months.

Report Available

2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

85613