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HelpTest ID CRCOF Chromium and Cobalt, Synovial Fluid
Ordering Guidance
This test should only be used in individuals with chromium or cobalt implants.
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.
Supplies: Metal Free EDTA 3mL Tube (T989)
Container/Tube: Royal blue-top BD vacutainer with EDTA blood collection tube (3 mL) (BD catalog no. 367777) (T989)
Specimen Volume: 1 mL
Collection Instructions: See Metals Analysis Specimen Collection and Transport for complete instructions.
Additional Information: Cobalt and chromium are present in the black rubber plunger seals found in most disposable syringes. As a result, synovial fluid should not be collected in these devices as contamination may occur.
Secondary ID
606424Useful For
Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs
This test is not useful for assessment of vitamin B12 activity.
Special Instructions
Specimen Type
Synovial FluidSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Synovial Fluid | Refrigerated (preferred) | 90 days |
| Ambient | 90 days | |
| Frozen | 90 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
CHROMIUM:
0-17 years: Not established
≥18 years: <16.9 ng/mL
COBALT:
0-17 years: Not established
≥18 years: <19.8 ng/mL
Day(s) Performed
Friday
Report Available
2 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83018
82495