Test ID APTTP Activated Partial Thromboplastin Time, Plasma
Secondary ID
40935Useful For
Monitoring heparin therapy (unfractionated heparin)
Screening for certain coagulation factor deficiencies
Detection of coagulation inhibitors such as lupus anticoagulant, specific factor inhibitors, and nonspecific inhibitors
Specimen Type
Plasma Na CitOrdering Guidance
The primary method for therapeutic heparin monitoring is the heparin anti-Xa assay. Order HEPTP / Heparin Anti-Xa Assay, Plasma.
Specimen Required
Specimen Type: Platelet-poor plasma
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge, remove plasma and centrifuge plasma again.
2. Aliquot plasma into plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
Additional Information: Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma Na Cit | Frozen (preferred) | 30 days |
| Ambient | 4 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
25-37 seconds
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 dayPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85730