Test ID ANA2 Antinuclear Antibodies (ANA), Serum
Useful For
Evaluating patients at-risk for antinuclear antibodies-associated systemic autoimmune rheumatic disease particularly systemic lupus erythematosus, Sjogren syndrome, and mixed connective tissue disease
Testing Algorithm
For more information see Connective Tissue Disease Cascade.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
If suspicious of connective tissue disorder, see CTDC / Connective Tissue Disease Cascade, Serum.
If suspicious of autoimmune liver disease, see ALDG2 / Autoimmune Liver Disease Panel, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Special Instructions
Reference Values
Negative: ≤1.0 U
Weakly positive: 1.1-2.9 U
Positive: 3.0-5.9 U
Strongly positive: ≥6.0 U
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
CPT Code Information
86038
Report Available
1 dayReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
-Gastroenterology and Hepatology Test Request (T728)
-Kidney Transplant Test Request
-Renal Diagnostics Test Request (T830)