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Test ID ADNAP Double-Stranded DNA (dsDNA) Antibodies Panel, IgG, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

620812

Useful For

Evaluation of patients at-risk of systemic lupus for erythematosus (SLE) with abnormal antinuclear antibodies

 

Management of affected individuals

 

Distinguishing SLE from other autoimmune diseases

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
CRTHT dsDNA Ab IFA Titer, IgG, S No No

Testing Algorithm

If the double-stranded DNA (dsDNA) IgG antibodies Crithidia luciliae immunofluorescence screen is positive, then the dsDNA IgG antibodies Crithidia luciliae immunofluorescence titer will be performed at an additional charge.

 

For more information see Connective Tissue Disease Cascade.

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-Treated Reject

Reference Values

DOUBLE-STRANDED DNA (dsDNA) ANTIBODIES, IgG:

<100 IU/mL (Negative)

≥100 IU/mL (Positive)

Negative is considered normal.

Reference values apply to all ages.

 

DOUBLE-STRANDED DNA (dsDNA) IgG ANTIBODIES, CRITHIDIA LUCILIAE IMMUNOFLUORESCENCE SCREEN

Negative (<1:10)

Reference values apply to all ages.

 

DOUBLE-STRANDED DNA (dsDNA) IgG ANTIBODIES, CRITHIDIA LUCILIAE IMMUNOFLUORESCENCE TITER

Negative (<1:10)

Day(s) Performed

ADNA1: Monday through Saturday

CRTHS, CRTHT: Monday through Friday

Report Available

2 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

ADNA1-86225

CRTHS-86255