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HelpTest ID A1ALC Alpha-1-Antitrypsin Proteotype S/Z, LC-MS/MS, Serum
Useful For
Identification of homozygous and heterozygous S and Z proteotypes of alpha-1-antitrypsin deficiency
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| A1APR | Alpha-1-Antitrypsin Phenotype, S | Yes, (order A1APP) | No |
Testing Algorithm
If the mass spectrometry proteotype and quantitative serum level are discordant, then phenotyping will be added and performed at an additional charge.
For more information see Alpha-1-Antitrypsin-A Comprehensive Testing Algorithm
Special Instructions
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.25 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Reference Values
ALPHA-1-ANTITRYPSIN:
100-190 mg/dL
ALPHA-1-ANTITRYPSIN PROTEOTYPE:
Negative for S and Z phenotype (Non S Non Z)
Day(s) Performed
Monday, Thursday
Report Available
7 to 14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82103
82542
82104 (if appropriate)
Forms
If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.